{"head\/og\/url":"podcasts\/young-women-are-protected-against-vascular-insulin-resistance-induced-by-adoption-of-an-obesogenic-lifestyle-4zXyLE1GC","head\/title":"Young women are protected against vascular insulin resistance induced by adoption of an obesogenic lifestyle","head\/description":"Vascular insulin resistance is a feature of obesity and type 2 diabetes that contributes to the genesis of vascular disease and glycemic dysregulation. Data from preclinical models indicate that vascular insulin resistance is an early event in the disease course preceding the development of insulin resistance in metabolically-active tissues. Whether this is translatable to humans requires further investigation. To this end, we examined if vascular insulin resistance develops when young healthy individuals (n=18 men, n=18 women) transition to an obesogenic lifestyle that would ultimately cause whole-body insulin resistance. ","head\/og\/image":"https:\/\/media.podscholars.com\/f\/podcasts\/4zXyLE1GC.jpg","podcast":{"ID":7,"status":40,"date_created":"2022-10-06 00:01:21","owner_ID":16,"article_ID":7,"audience_type":0,"stats_view":1379,"stats_like":13,"stats_save":0,"stats_play":0,"title":"Young women are protected against vascular insulin resistance induced by adoption of an obesogenic lifestyle","abstract":"Vascular insulin resistance is a feature of obesity and type 2 diabetes that contributes to the genesis of vascular disease and glycemic dysregulation. Data from preclinical models indicate that vascular insulin resistance is an early event in the disease course preceding the development of insulin resistance in metabolically-active tissues. Whether this is translatable to humans requires further investigation. To this end, we examined if vascular insulin resistance develops when young healthy individuals (n=18 men, n=18 women) transition to an obesogenic lifestyle that would ultimately cause whole-body insulin resistance. ","duration":1047,"file_audio":null,"file_video":"633dfeb07144e.mp4","compressed":1,"author_firstname":"James","author_lastname":"Smith","article_date":2022,"article_DOI":"https:\/\/academic.oup.com\/endo\/article-abstract\/163\/11\/bqac137\/6668857","publication_ID":7,"publication_name":"Endocrinology","author_slug":"james-smith-4zXyLE1GL","publication_slug":"endocrinology-4zXyLE1GC","keywords":[{"name":"sedentary behavior","slug":"sedentary-behavior-4zXyLE1GS"},{"name":"sugar-sweetened beverages","slug":"sugar-sweetened-beverages-4zXyLE1GT"},{"name":"endothelial dysfunction","slug":"endothelial-dysfunction-4zXyLE1GU"},{"name":"blood flow","slug":"blood-flow-4zXyLE1GV"},{"name":"sex differences","slug":"sex-differences-4zXyLE1GW"}],"disciplines":[{"name":"Medical and Health Sciences","slug":"medical-and-health-sciences-4zXyLE1GG"},{"name":"Physiology","slug":"physiology-4zXyLE1Hs"},{"name":"Clinical Sciences","slug":"clinical-sciences-4zXyLE1Ic"}],"publication_authors":[],"authors_links":[],"slug":"young-women-are-protected-against-vascular-insulin-resistance-induced-by-adoption-of-an-obesogenic-lifestyle-4zXyLE1GC"}}